Associated inactivated emulsion vaccine against bovine viral diarrhea, bovine parainfluenza-3 and infectious bovine rhinotracheitis

Description

Vaccine is intended for bovine parainfluenza-3 (BPI-3), infectious bovine rhinotracheitis (IBR) and bovine viral diarrhea (BVD) prevention on farms infected with and farms at risk of these diseases. The vaccine dosage form is an emulsion for injections. The vaccine is a homogeneous emulsion of white or white-pink colour. Slight emulsion creaming at the top of the bottle during its storage is admissible. The emulsion becomes homogeneous again after thorough shaking.

Indications

The vaccine is intended for bovine viral diarrhea (BVD), bovine parainfluenza-3 (BPI-3) and infectious bovine rhinotracheitis (IBR) prevention on farms infected with and at risk of the said diseases.

Route of administration

Only clinically healthy animals should be vaccinated.

The vaccination is contraindicated in case of acute infectious diseases on the farm. The vaccination of emaciated and/or weakened animals is not allowed.

The vaccine is administered intramuscularly in the middle third of the neck. The site of injection is treated with 70% ethanol or other disinfecting

solution. The vaccine should be warmed in a water bath up to 30 – 35 °C for 10-15 minutes before administration. The vaccine bottles should be regularly shaken during the vaccination procedure.

The volume of the vaccine dose is 2 cm3. Disposable or reusable syringes and needles as well as autoinjectors sterilized by boiling in water for 15-20 min should be used for the vaccination. Sterilization of syringes, needles and autoinjectors with chemicals is prohibited.

For the specific disease prevention on the farm at first all cattle of various ages should be vaccinated twice with a 21-30 day interval. Then, the animals should be revaccinated by single vaccine administration 6 months after. Calves should be vaccinated at the age of 1-3 days or older; down-calving heifers and cows should be vaccinated 50-45 days and 20-25 days prior calving, respectively; heifers ready for breeding should be vaccinated 1.0-1.5 month prior to the first service.

Immunity

The vaccine induces the immune response in cattle to bovine viral diarrhea, bovine parainfluenza-3 and infectious bovine rhinotracheitis viruses on day 14-21 after the second vaccination. The immunity lasts for at least 6 months.

Storage conditions

The vaccine should be stored and transported in dry dark place at 2 – 8 °C. Freezing of the vaccine is not allowed. The vaccine shelf life is 12 months from the date of its production provided that its storage and transportation conditions are met.

Disease: 
bovine vir al diarrhea (BVD), bovine parainfluenza-3 (BPI-3), infectious bovine rhinotracheitis (IBR)
Strain/ serotype: 
NADL-ARRIAH/VGNKI-4/ ARRIAH
Appearance: 
inactivated emulsion
Filling/ dosage: 
10 and 100 cm3 bottles
Measurement unit: 
one thousand doses
Instructions: 
Certificates: