Liquid sorbate inactivated vaccine against infectious bursal disease

Indications

The vaccine is intended for vaccination of replacement chickens for grandparent and parent stocks (broilers and egg-laying chickens) on different types of IBD free farms and farms at IBD risk as well as on IBD infected farms for establishment of passive maternal immunity in chickens.

Formulation

The vaccine is manufactured from homogenated SPF-chicken embryos infected with IBD virus (BG and K-58 strains) inactivated with aminoethylethanolamine dimer. Aluminum hydroxide is added as a sorbing agent and saponin is added as an adjuvant.

Biological properties

The vaccine induces immune response against infectious bursal disease in chickens in 14–21 days post single administration. The immunity lasts for 3 months. The vaccination is considered successful in case at least of 80% of vaccinated birds demonstrate antibody titer of at least 1:2 in DPT or ELISA titer is at least twice as high as minimal positive value prescribed in the manufacturer’s instruction to the test-kit. If the immunity level is low in more than 80% of birds the chickens should be revaccinated. The vaccine is innocuous and has no therapeutic properties.

Route of administration

Vaccine is administered to 70–110-day-old replacement chickens. The vaccine is administered intramuscularly in a thigh or breast at a dose of 0.5 cm3. Before administration the vaccine is left at 20°C for 6–9 hours. Do not heat the vaccine on the water-bath or heating appliances. Before and during administration the bottle with the vaccine should be repeatedly shaken in order to maintain the suspension homogeneity. Disposable and reusable syringes and needles should be used for vaccination. Reusable syringes and needles should be sterilized by boiling for 15–20 min. Do not sterilize syringes and needles using any chemical agents. The injection site should be disinfected with 70% ethanol or other disinfecting solution. In 14–21 days post vaccination the immunity level should be controlled by testing of at least 20 blood samples.

Shelf-life

and storage conditions

The vaccine shelf-life is 12 months from the date of production in case storage and shipment conditions are followed. Do not use the vaccine after expiry date. The vaccine should be stored and transported in a dry and dark place at 2–8°C. Avoid vaccine freezing.

Disease: 
IBD
Strain/ serotype: 
BG
Appearance: 
liquid, inactivated
Filling/ dosage: 
50, 100, 200, 250, 500 cm3 bottles
Measurement unit: 
one thousand doses
Instructions: 
Certificates: