MARIVAK 1+3 virus vaccine against Marek’s disease


The vaccine is a horizontally-levelled frozen homogenous mass, when thawed is a yellowish pink opalescent suspension without any sediment. Marketed in Dewar f lasks filled with liquid nitrogen.


The vaccine is indicated for the prevention of Marek’s disease on breeding and commercial poultry farms of different types. Clinically healthy dayold chicks (during their first hours of life) are subject to vaccination.

Route of administration

Dilute the vaccine using the diluent according to MARIVAK 1+3 virus vaccine package leaflet and inject intramuscularly into the upper third of the inner thigh or subcutaneously into the neck in the amount of 0.2 ml of eac h chick.


A single vaccination induces MDV immunity in chicks on 14–21 day post vaccination which lasts during the whole laying period of the bird.

Storage conditions

The shelf life of the vaccine and diluent is 24 months provided the storage and transportation conditions are met. The vaccine should be stored in liquid nitrogen at –196°C. Refreezing and thawing of the vaccine as well as its storage in liquid nitrogen vapour is not allowed. When the shelf life is expired the virus vaccine and diluent shall not be used. The diluent should be stored in a dry dark place at 4–20°C.

Marek’s disease
Strain/ serotype: 
3004 and VL ADIMIR / Serotypes 1 and 3
Virus vaccine
Filling/ dosage: 
Ampoule, 2 cm 3
Measurement unit: 
one thousand doses